Recent Studies Link Statins with Better Periodontal Disease Outcomes

Peridontal Disease Outcomes

Share This Post

Recent studies conducted by the American Society for Biochemistry and Molecular Biology have found that statins (a class of drug commonly used to reduce cholesterol) are showing promise for better periodontal disease outcomes. Subramanya Pandruvada, assistant professor in the College of Dental Medicine at the Medical University of South Carolina led the study and recently addressed Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology, held in San Antonio.

Most people are probably at least familiar with drugs that are used to treat high cholesterol. The most common family of drugs used to treat these conditions are statins. Crestor and Lipitor are two names you may have heard and these two drugs are part of the statin family. These drugs specifically help lower LDL (“bad cholesterol”) and are among the most prescribed drugs on the market today.

Testing Methodology

Dr. Pandruvada created the study by creating cell cultures that replicate the conditions of periodontal disease and then observing the effects produced when statins were introduced to the mix. According to Dr. Pandruvada:

“During our study, we replicated specific conditions in periodontal disease and demonstrated that introducing statins to our in vitro model modifies macrophage response. This allowed us to explore how medication like statins can help us treat inflammatory conditions such as periodontal disease.”

For some background, periodontal disease occurs when our immune system reacts to excessive bacteria growth around our teeth and gums. One component of our immune system, macrophages, can overreact and cause inflammation, swelling and bone degradation. Sadly, periodontal disease is quite common, affecting 50% of adults over age 30. And while treating this condition with antibiotics and deep cleanings is effective, this new development would be a great step forward. Reducing the frequency that doctors have to prescribe antibiotics would have additional benefits of increasing our overall immune system health.

Statins Are Promising For Peridontal Disease Outcomes

Statins may offer a less invasive treatment strategy for periodontal disease by calming gum disease. Previous studies have hinted at fewer signs of periodontitis in individuals taking statins. Dr. Pandruvada’s study is the first to explore the biochemical pathways through which statins mitigate periodontal inflammation, emphasizing their effect on macrophages.

To find out more about how to prevent and treat periodontal disease, contact our office today. Then schedule an appointment and help keep your smile healthy and beautiful.

Read the full article here.

More To Explore

You Are Welcome Here.

Schedule your consultation today.